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Platelet-Rich Plasma

  • The fraction (portion) of blood containing a high concentration of platelets, additional growth factors and bioactive molecules

  • Provides the raw materials needed for healing injured, damaged tissue within or around joints and tendons at supra-physiologic concentrations

Image by ANIRUDH

  • This process supports tissue repair by releasing platelet-derived growth factors, cytokines, signaling molecules, and adhesive proteins that aid in regeneration.

  • After platelet-rich plasma (PRP) treatment, local tissue regulators further enhance musculoskeletal healing by promoting communication between cells through specialized (paracrine, autocrine) signaling mechanisms.

Targeted delivery of concentrated platelets into injured or damaged musculoskeletal tissues can activate natural healing pathways

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What Happens Inside Joints after PRP Injection?

Release of bioactive molecules in the joint space

Microscopic Reactions

Significant Changes

Cartilage lesions appear healthier

Joints appear less inflamed

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Exhibits chondroprotective effect

No disease progression

> 95% of Participants Report:​

  • Alleviated pain

  • Improved function

  • Improved quality of life

The Role of Platelet-Rich Plasma in Inducing Musculoskeletal Tissue Healing

(b) No disease progression 1 year after PRP injection 

(a) high-grade partial thickness wear over the medial femoral condyle (thick arrow) and tibial plateau with bone spurs (thin arrows). 

Image by ANIRUDH

Arthrex PRP System

  • Rapid, efficient concentration of platelets and growth factors from a patient’s blood,

  • Unique double-syringe design for safe, minimally invasive, point-of-care treatment

  • Accelerates healing, reduces inflammation, and enhances tissue repair

  • The closed system minimizes contamination risk, increases platelet concentration, and streamlines the PRP preparation process, yielding robust results in tissue regeneration and pain reduction

What Happens Inside Tendons after PRP Injection?

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a) Significant tendinosis of the common extensor origin (thick arrow) with a partial thickness intrasubstance tear (thin arrow) and adjacent extracapsular soft tissue edema (short arrow).

b) Follow up MRI 3 months after PRP, there is only mild tendinosis (white arrow) with resolution of the previously seen partial thickness tear.

Want to Learn More? Here's What The Research Shows Us: 

How It's Done

Hover For Descriptions

The Big Picture:

Lasting pain relief

Better function

Improved quality of life

Without the need for surgery or significant downtime. 

We Can't Wait To Make You Better.

Call us today to schedule your appointment or for more information!

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145 Rosemary Street, Suite J

Needham, MA  02494

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 Phone     (781) 429-7700

Fax           (781) 429-7701

Ortho.Boston
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